Splice (2009) Review
Splice is about two biochemists, Clive and Elsa (Adrian Brody and Sarah Polley) who mix animal DNA together to make hybrids. They hope to create something that will help cure diseases in people, but the work is tricky. They successfully make two worm-like creatures, nicknamed Ginger and Fred, then move on to phase two: a human-animal hybrid. The result is a creature they come to call Dren, which must be kept secret from their employers, because it’s illegal, but Dren matures much faster than they anticipate. She creates a divide between the two scientists , and drives them to their breaking points.

These two characters are like 21st century
Frankenstein’s. They defile the rules other scientists follow, create a
creature that doesn’t know why it’s alive, and try to hide it from others while
learning about it and caring for it. Dren is made to be a fairly sympathetic
creature, but her design is just outside the realm of sympathy, for me. Her
eyes are spaced wide apart, her legs are like a horse's mixed with a frog mixed
with a rat, and she has a spike-tipped tail. Elsa treats Dren like her own
child, but Clive wanted to have a baby with Elsa the old fashioned way, which
she was opposed to. There’s definitely an interesting (and twisted) theme of
parenthood and creation threaded throughout the story.

While it is a very strange and entertaining movie, Splice isn’t particularly exceptional.
The cgi effects are not top notch by any means, the characters often make
idiotic decisions, many concepts are derivative of other better sci-fi films,
and it sort of devolves into standard monster movie conventions toward the end.
In spite of all that, it takes what could have been a fairly generic premise
and spins it in a unique way that makes it worth checking out, especially if
off-kilter-sci-fi horror is your thing.
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